منابع مشابه
Diamine oxidase and cadaverine metabolism.
We have recently presented evidence that diamine oxidase is rcsponsiblc for a portion of the metabolism of histamine in several species (1, 2). This evidence is largely based on the alteration of histamine metabolism produced by compounds which are known to inhibit diamine oxidase in vitro. The inhibitors used were isonicotinylhydrazine (3) and aminoguanidine. The latter is reported to be the m...
متن کاملIdentifying human diamine sensors for death related putrescine and cadaverine molecules
Pungent chemical compounds originating from decaying tissue are strong drivers of animal behavior. Two of the best-characterized death smell components are putrescine (PUT) and cadaverine (CAD), foul-smelling molecules produced by decarboxylation of amino acids during decomposition. These volatile polyamines act as 'necromones', triggering avoidance or attractive responses, which are fundamenta...
متن کاملDiamine oxidase activity levels in anorexia nervosa.
OBJECTIVE Anorexia nervosa (AN) patients often experience gastrointestinal complications caused by their malnutrition. We hypothesized that intestinal integrity is disturbed in AN. Therefore, the objective of the present study was to investigate serum diamine oxidase (DAO) activity, which is considered to be a clinical indicator of the integrity of the intestinal mucosa, in AN patients. METHO...
متن کاملThe Inhibition of Human Placental Diamine Oxidase
1. The oxidation of p-dimethylaminomethylbenzylamine by purified placental diamine oxidase was followed by measuring the change in E250 caused by the production of p-dimethylaminomethylbenzaldehyde. 2. The inhibition of this reaction by substrate analogues such as isothiouronium, guanidinium, dimethylsulphonium and trimethylammonium compounds was extensively studied. 3. The type and degree of i...
متن کاملCadaverine, an Essential Diamine for the Normal Root Development of Germinating Soybean (Glycine max) Seeds.
When the polyamine content of soybean (Glycine max) seeds was examined during the early stages of germination, the major polyamine in the cotyledons was found to be spermidine, followed by spermine; while very low concentrations of cadaverine were found. In the embryonic axes, however, cadaverine was the main polyamine and its content markedly increased 24 hours after the start of germination. ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1954
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)71337-9